Human C-reactive Protein (CRP) Gene 1059 G > C Polymorphism is Associated with Plasma CRP Concentration in Patients Receiving Coronary Angiography

C-reactive protein + 1059 G>C polymorphism in type 2 diabetes and coronary artery disease patients☆

Human C-reactive protein (CRP) is an acute phase reactant involved in chronic and acute inflammation. CRP is associated with metabolic syndrome, obesity, atherosclerosis, unstable angina, insulin resistance and diabetes. The present study evaluates the association of + 1059 G>C silent polymorphism in exon 2 of CRP gene in 581 cases [CAD (206), T2D (266), T2D with CAD (109)] and 235 controls in ...

C-reactive protein: CRP IL-6 homocysteine.

Association of common C-reactive protein (CRP) gene polymorphisms with baseline plasma CRP levels and fenofibrate response: the GOLDN study.

OBJECTIVE C-reactive protein (CRP) is an inflammatory marker that contributes to the prediction of cardiovascular disease. We investigated the influences of CRP polymorphisms on baseline CRP levels and fenofibrate-induced CRP changes in subjects with the metabolic syndrome. RESEARCH DESIGN AND METHODS We examined the association of CRP single nucleotide polymorphisms (SNPs) (m772A>G, m301G>A ...

Variation in the C-reactive protein gene is associated with serum levels of CRP in patients with acute ischemic stroke.

BACKGROUND AND PURPOSE Elevated levels of C-reactive protein (CRP) are found in up to three quarters of patients with acute ischemic stroke and are associated with poor outcome. We investigated whether haplotypes representing common variations in the CRP gene are associated with levels of CRP in patients with acute ischemic stroke. METHODS We included 185 patients with ischemic stroke in whom...

Association of C-reactive protein (CRP) gene polymorphisms, serum CRP levels and cervical cancer prognosis.

BACKGROUND C-reactive protein (CRP) is the prototypical biomarker of inflammation. Genetic variations within the CRP gene have been shown to be associated with alterations of CRP expression and prognosis in cancer patients. The purpose of this study was to evaluate the association between four polymorphisms of the CRP gene, CRP serum levels, clinicopathological parameters of cervical cancer and...